个人简介熊锡山，男，主治医师，讲师，30岁。曾师从中华医学会肾脏病分会副主任委员、上海市肾脏病分会主任委员梅长林教授，2008年6月底获第二军医大学肾脏病学博士学位，毕业后分配至军事医学科学院附属医院肾内科，现职称是主治医师。曾参与完成了多项科研课题：一、新型酪氨酸激酶抑制剂的研发和治疗多囊肾病的实验研究(国家科技部863项目编号:2002AA2Z3130金额300万)；二、PPARγ激动剂的研发及治疗多囊肾病实验研究(国家科技部863项目编号:2007AA02Z3Z1金额50万)。以第一作者身份共发表SCI收录论著5篇，以共同第一作者身份发表SCI收录论著1篇，以其他作者身份发表SCI收录论著5篇。获得专利2项，多年从事肾脏病基础及临床研究，对各种常见肾脏疾病、急慢性肾功能不全、血液净化、多囊肾病的临床救治，经验丰富。目前已发表的文章:1.Pyrimidinyl-arylpropionicacidderivatives:viableresourcesinthedevelopmentofnewantineoplasticagents.XiongXishan,WangL,YeY,FuL,ChenM,WangQ,LiuM,TangJ,DaiB,ShenJ,MeiC.InvestNewDrugs.2009Jun17.[Epubaheadofprint]2.B5,anovelpyrrole-substitutedindolinone,exertspotentantitumorefficacythroughG2/Mcellcyclearrest.XiongXishan,ZhangY,GaoX,DongZ,LiL,JiC,FuL,LuoX,LiuH,MeiC.InvestNewDrugs.2010Feb;28(1):26-34.Epub2009Jan13.3.AntitumoractivityofanewN-substitutedthioureaderivative,anEGFRsignaling-targetedinhibitoragainstapanelofhumanlungcancercelllines.XiongXishan,LiuH,FuL,LiL,LiJ,LuoX,MeiC.Chemotherapy.2008;54(6):463-74.Epub2008Oct2.4.Antitumoractivityofanovelseriesofalpha-aryloxy-alpha-methylhydrocinnamicacidderivativesasPPARgammaagonistsagainstapanelofhumancancercelllines.XiongXishan,YeY,FuL,DaiB,LiuJ,JiaJ,TangJ,LiL,WangL,ShenJ,MeiC.InvestNewDrugs.2009Jun;27(3):223-32.Epub2008Aug13.5.AntitumoractivityofanovelEGFRtyrosinekinaseinhibitoragainsthumanlungcarcinomainvitroandinvivo.XiongXishan,FuL,WangL,CaiH,LiL,JiangH,DuanW,MeiC.InvestNewDrugs.2009Feb;27(1):1-11.Epub2008May21.6.Antitumorefficacyoftwonovelnon-thiazolidinedionecompoundsasperoxisomeproliferator-activatedreceptor-gammaagonistsinhumanosteosarcomacellsinvitro.FuL,XiongXishan,WangL,GaoX,YeY,JiaJ,HuH,LiL,ShenJ,MeiC.Chemotherapy.2009;55(6):468-76.Epub2009Dec9.7.MycophenolatemofetilversusRapamycininHan:SPRDratswithPolycysticKidneyDisease.ZhangT,WangL,XiongXishan,MaoZ,WangL,MeiC.BiolRes.2009;42(4):437-44.Epub2010Jan29.8.DH9,anovelPPARgammaagonistsuppressestheproliferationofADPKDepithelialcells:Anassociationwithaninhibitionofbeta-cateninsignaling.LiuM,FuL,LiuC,XiongXishan,GaoX,XiaoM,CaiH,HuH,WangX,MeiC.InvestNewDrugs.2009Sep16.[Epubaheadofprint]9.Identificationofphosphoproteinsinkidneytissuesfrompatientswithautosomaldominantpolycystickidneydisease.YaweiLiu,BingDai,ChanglinMei,YanZhang,XiongXishan,RichardSandford.Proteomics-ClinicalApplications.Volume2Issue7-8,Pages1153-116610.Design,synthesisandantitumorevaluationofanewseriesofN-substituted-thioureaderivatives..LiJ,TanJZ,ChenLL,ZhangJ,ShenX,MeiCL,FuLL,LinLP,DingJ